Ribbon structure of the BRCA2 protein. Mutations in the BRCA2 gene are linked to increased risk of breast cancer. New work from UC Davis shows how individual BRCA2 proteins work to repair damaged DNA, ...

Add Yahoo as a preferred source to see more of our stories on Google. FILE PHOTO: A radiologist examines breast X-rays after a cancer prevention medical check-up at the Ambroise Pare hospital in ...

The FDA approved niraparib and abiraterone acetate (Akeega) in combination with prednisone for treating BRCA2-mutated metastatic castration-sensitive prostate cancer (mCSPC), the agency announced on ...

The breast cancer type 2 susceptibility (BRCA2) protein, which is frequently mutated in hereditary breast cancer, is involved in the repair of DNA double-strand breaks by homologous recombination ...

BRCA2 is one of the best-known genes associated with breast and ovarian cancer, yet we know remarkably little about its role in the cell. Despite its large size (390 kDa), BRCA2 contains no obvious ...

Zoe Wilson thought she may be at risk. It wasn’t just a vague gut feeling: the risk was demonstrable and clear, running ...

Authors in the Journal of Clinical Oncology discuss hypotheses on the differences in mutations and implications for treatment with PARP inhibitors. The year 2020 was a watershed in prostate cancer ...

Researchers from the U.K. and the U.S. have called for immediate action to recommend screening for prostate cancer for men with BRCA2 mutations over the age of 40 after presenting the results of a new ...

The study showed that oxidative stress, which is considered to contribute to cancer development, actually suppressed cancer in rats with BRCA2 gene mutations. Oxidative stress is considered to ...

For decades, it has been known that the mutations in the tumor suppressor genes BRCA1 and BRCA2 are associated with high risks of breast and ovarian cancer, but a new prospective cohort study provides ...

Telling a child about their mother's risk of hereditary breast and ovarian cancer does not adversely influence the offspring's lifestyle or quality of life in the long term, according to a new study ...

new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA. By studying BRCA2 at the level of single molecules, researchers at ...