Extrachromosomal circular DNA (ecDNA) represents a distinct genomic entity that exists independent of the primary chromosomal structure. In cancer, ecDNA is recognised as a potent driver of oncogene ...
Figure 1. Design and synthesis of circAMO . (a) Synthesis of a single-molecule ring by rigid regulation of selectivity; (b) Schematic diagram of circAMO design; (c) Synthesis of circAMO; (d) ...