A deep dive into the Fc–FcR axis as a therapeutic anchor in autoimmune disease, examining immune signaling and drug ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
The engineering and functional characterization of the Fc domain are key to therapeutic antibodies’ efficacy, safety, and pharmacokinetics. The Fc domain is responsible for mediating interactions with ...
Immunoglobulins are central to shaping immune responses and are critical tools for probing biological mechanisms in biomedical research. However, selecting an inappropriate antibody isotype can lead ...
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