Integrated analytical workflows are transforming cell line development by combining faster screening and streamlined decision-making.

Modern therapeutics are shifting from their reliance on small molecules to biologics produced by cultured cells. The development and production of those biologics increasingly rely on computationally ...

Scientists have developed a way to engineer immune cells that specifically target tumors. The application of engineering cells first appeared in the 1980s, but the concept has significantly progressed ...

Regenerative medicine combines tissue engineering and cell therapies to repair or replace damaged human tissues and organs. Key applications include treating osteoarthritis with mesenchymal stem cells ...

Michel Sadelain, a global pioneer in CAR T-cell immunotherapy, will head the new Columbia Initiative in Cell Engineering and Therapy. Interim University President Katrina Armstrong announced the ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide ...

Although Chinese hamster ovary (CHO) cells have dominated therapeutic protein expression systems for decades, biomanufacturers still must deal with their inconsistent expression levels and varying ...

Viruses are effective tools for delivering genetic material into cells, and scientists have taken advantage of viral transduction in numerous ways, such as constructing chimeric antigen receptor (CAR) ...

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. Current approved CAR T-cell therapy treatments rely ...