G protein-coupled receptors (GPCRs) are seminal transducers of extracellular signals into intracellular responses, orchestrating intricate cascades that regulate cell proliferation, migration and ...

G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors, orchestrating a vast array of physiological responses by transducing extracellular signals into ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...

A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

Infectious diseases are illnesses caused by pathogenic microorganisms—including viruses, bacteria, fungi, and parasites—that invade a host, replicate, and ...

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...

Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...

Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...

New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses. However ...