Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine and arginine ...

Histidine decarboxylase is one of the enzymes of the amine precursor uptake and decarboxylation system and is known to be distributed in mast cells and enterochromaffin-like cells. With the hypothesis ...

Tsukuba, Japan—In eukaryotes, genomic DNA, which is a very long double helix containing all the genetic information, wraps around a globular protein called a histone and folds it many times before ...

Radiation Research publishes articles dealing with radiation effects and related subjects in the areas of physics, chemistry, biology and medicine, including epidemiology and translational research.

Protein phosphorylation helps control most processes in cells. Phosphorylation most often occurs at serine, threonine, or tyrosine residues in proteins. Histidine residues also can be phosphorylated, ...

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" ...

A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions. A ...

Suitable for bioprocessing, solubilization, and stabilization applications, the new histidine products allow for the control of endotoxin and trace metal impurities reflected with elemental impurity ...