The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

The university's scientists have received a $28.5 million award from the Advanced Research Projects Agency for Health to develop a transplantable 3D-printed liver patch. The initiative ...

"At one level, it shows that we have taken a significant step forward at growing liver tissue in the lab that accurately mimic human liver function. While human liver organoid transplantation remains ...

In a human organoid-based mechanistic investigation, researchers revealed how an immunosuppressive drug, antithymocyte ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the ...

A pig's liver has been transplanted into a human recipient for the first time in a ‘milestone’ for organ transfers between animals and people. Scientists in China used a liver taken from a seven-month ...

Our liver has admirable regenerative properties. But it takes a beating every day. Eventually, its tissues scar, and if the organ fails, a liver transplant is the only solution. Donor livers are hard ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...