Monoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of these biologics is the extent and rate of internalization into different ...
Antibody-Drug Conjugates (ADCs) are a fundamental technology in modern tumor-targeted therapy with their ‘tripartite integrated design’ of ‘precision carrier - stable linker - potent payload’: The ...
G protein-coupled receptors (GPCR) are a large and diverse class of plasma membrane receptors involved in transduction of extracellular signals. The range of GPCR ligands is broad and includes small ...
The MarketWatch News Department was not involved in the creation of this content. CUSABIO Launches DT3C to Streamline Antibody Screening and Enhance ADC Research HOUSTON, March 7, 2025 ...
Antibody internalization underpins applications from ADC delivery to receptor modulation. This application note presents a live-cell, no-wash assay using a pH-sensitive Fab-based labeling dye to ...
CD37, a surface protein present on most acute myeloid leukemia (AML) blasts, demonstrates unique internalization properties that enable targeted drug delivery with minimal impact on normal blood cells ...
Fluorescence imaging offers robust, multi-parametric and scalable analysis of cell-level activity in heterogenous populations with excellent spatial and temporal resolution. This seminar will provide ...
Liquid biopsy next-generation sequencing (NGS) assays help guide treatment selection in cancer patients, particularly when tumor tissue is unavailable or during disease progression. Extensive ...
Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such long blood circulation, specific molecular recognition, and ...
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