Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

Fats are an important part of the human diet as a major source of energy. Around 90% of the fat stores are on top of muscle, so just under the skin. However, excessive dietary fat intake leads to fat ...

If you are generally healthy, your body does not need a reset as the liver works best with time and consistency, meaning fewer repeated stresses and enough recovery time to heal and function properly ...

Over time, this damages liver cells, triggers inflammation and contributes to fibrosis, which is the build-up of scar tissue. If scarring becomes extensive, it can progress to cirrhosis, a stage where ...

The liver and pancreas are organs in the upper abdomen. The liver is vital for metabolism, detoxification, digestion, and more. The pancreas produces essential enzymes and hormones. Together, they ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the ...