A biomarker test identified tau pathology in Alzheimer's disease before fibrillary tangles developed. Neurofibrillary tangle formation can be prevented by targeting intermediate soluble tau assemblies ...

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, ...

Why do memories falter with age? In a preprint posted on bioRxiv on May 22, scientists led by Omer Sharon and sleep researcher Matthew Walker at the University of California, Berkeley, suggested that ...

Today we begin a several-part series on Alzheimer’s disease, the most common cause of memory loss and dementia. Alzheimer’s is a brain disease characterized by amyloid plaques and neurofibrillary ...

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease progression is ...

Down syndrome is caused by an extra copy of chromosome 21. Because of genes present on this chromosome that are known to contribute to Alzheimer's disease, patients with Down syndrome often develop ...