Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...
Dr. Kaneez Fatima Shad knows that the “Patch Clamp” method needs skills and patience. It takes the whole day to craft only one sample and even a small leak could alter the results drastically.
In 1991, Bert Sakmann and Erwin Neher were awarded the Nobel Prize in Physiology or Medicine for their discoveries on the function of ion channels, which were made possible by their development of ...
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