The goal of the study is to investigate host genetic and immunologic predictors of resistance to M. tuberculosis infection and progression from latent M. tuberculosis infection to active tuberculosis ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of ...

CHAPEL HILL -- New research led by a University of North Carolina at Chapel Hill scientist shows for the first time how Mycobacterium tuberculosis, the germ responsible for TB, uses a system for ...

A sugar on mycobacteria binds to the immune receptor dectin-1 on host macrophages, helping the bacteria survive and driving susceptibility to infection.

Scientists discovered genes in the tuberculosis bacterium that becomes essential for the pathogen's survival when it's exposed to air through coughing. These genes could be targets for new therapies ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

Psychiatry has struggled to enter the precision medicine era. But through a mix of innovations and bootstrapping, progress is coming to the field. Scientists are ...

image: Jianjun Sun, Ph.D. left, associate professor in The University of Texas at El Paso Department of Biological Sciences, and Javier Aguilera, a doctoral student, stand in Sun's lab in the ...

Tuberculosis has plagued humanity for thousands of years, and despite medical advances that can now help us prevent and cure ...