With structural knowledge available of the over 80,000 macromolecular crystal structures recorded in the Protein Data Bank (PDB) 1, it should be feasible to solve the 'crystallographic phase problem' ...
The equilibrium distributions of hairpin ribozyme conformational isomers have been examined by time-resolved fluorescence resonance energy transfer. Ribozymes partition between active (docked) and ...
The origins of modern structural biology date back to the 1910s, when the German physicist Max von Laue discovered that biological crystal samples irradiated with X-rays produced diffraction patterns ...
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