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National Center for Case Study Teaching in Science
Fireflies and Firefly Bioluminescence
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The Enigmatic Dance of Fireflies: A Closer Look at Their Light-Producing Mechanism
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Feb 8, 2024
SOLVED: The enzyme called luciferase catalyzes the reaction that allows fireflies to emit light The first step in this reaction involves the substrate compound called luciferin , reacting with ATP. The luciferase enzyme has been crystallized bound to the product of this one-step reaction, as shown in the Pymol diagram below. (Dotted lines indicate stabilizing interactions between active site residues and the product:)HO_COzGln338luciferinNote:Lys529Blue nitrogen Red oxygen Orange sulfur or phos
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